u-Slim
Introduce
This novel weight control supplement contains optimal doses of Super CitriMax® (-) hydroxycitric acid from the dried fruit rind of Garcinia cambogia. Randomized, double-blind, placebo-controlled studies conducted by researchers at Georgetown University showed that 1,500 mg of Super CitriMax taken three times a day reduced weight loss 3-times greater than diet and exercise alone and increased fat burning, modified cholesterol levels and decreased body mass index.*
Super CitriMax® is a patented, 60% hydroxycitric acid (HCA) water extract from Garcinia cambogia. It is uniquely bound to calcium and potassium for maximum stability, solubility, bioavailability and efficacy. Super CitriMax® is an established brand supported by 4 peer-reviewed clinical research publications, and extensive safety research. Published research includes clinical studies on weight loss, appetite control, calorie reduction and lipid modulation. Published research also shows bioavailability in humans.*
- 3x more effective than diet and exercise alone*
- 44% increase in serotonin levels*
- 25% reduction in daily calorie intake*
- Self-affirmed GRAS
This product is only for distributors and wholesalers
- *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. The information provided on this site is intended for your general knowledge only and is not a substitute for professional medical advice or treatment for specific medical conditions.
Research
Here, you can read some of important published clinical research papers about Super CitriMax®, which support weight management. Published peer reviewed studies can be accessed through PubMed at www.ncbi.nlm.nih.gov/pubmed. For more information, please contact Renylin Bio-Health Inc.
Super CitriMax Treatment Reduced 24 h Energy Intake in Humans While Satiety Was Sustained
The effect of (-)-hydroxycitrate on
energy intake and satiety in overweight humans
Abstract
Objective: Assessment of the effects of 2 weeks of daily administration of HCA on energy intake and satiety in overweight men and women.
Design: A 6-week randomized placebo-controlled single-blinded cross-over trial.
Subjects: consumed three times daily for 2 weeks 100 ml tomato juice (placebo) and, separated by a 2 week wash-out period, 100 ml tomato juice with 300 mg HCA.Subjects: Twelve males and 12 females (body mass index 27.5+/-2.0 kg/m(2); age 37+/-10 y).
Mesurements: After 2 weeks, 24 h energy intake (EI), appetite profile, hedonics, mood and possible change in dietary restraint were assessed in the laboratory restaurant. Prevention of degradation and bio-availability was documented.
Results: Twenty-four-hour EI was decreased by 15-30% (P<0.05) with HCA treatment compared to placebo, without changes in the appetite profile, dietary restraint, mood, taste perception and hedonics, while body weight tended to decrease (P=0.1).
Conclusion: HCA treatment reduced 24 h EI in humans while satiety was sustained.
Source:
Westerterp-Plantenga MS, Kovacs EM.
Int J Obes Relat Metab Disord. 2002 Jun;26(6):870-2
www.ncbi.nlm.nih.gov/pubmed/12037659
Super CitriMax – Preuss, et al. Diabetes Obes Metab. 2004.
Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX)
and a combination of HCA-SX plus niacin-bound chromium
and Gymnema sylvestre extract on weight loss.
Abstract
AIM: The efficacy of optimal doses of highly bioavailable (-)-hydroxycitric acid (HCA-SX) alone and in combination with niacin-bound chromium (NBC) and a standardized Gymnema sylvestre extract (GSE) on weight loss in moderately obese subjects was evaluated by monitoring changes in body weight, body mass index (BMI), appetite, lipid profiles, serum leptin and excretion of urinary fat metabolites. HCA-SX has been shown to reduce appetite, inhibit fat synthesis and decrease body weight without stimulating the central nervous system. NBC has demonstrated its ability to maintain healthy insulin levels, while GSE has been shown to regulate weight loss and blood sugar levels.
METHODS: A randomized, double-blind, placebo-controlled human study was conducted in Elluru, India for 8 weeks in 60 moderately obese subjects (ages 21-50, BMI >26 kg/m(2)). Subjects were randomly divided into three groups. Group A was administered HCA-SX 4667 mg, group B was administered a combination of HCA-SX 4667 mg, NBC 4 mg and GSE 400 mg, while group C was given placebo daily in three equally divided doses 30-60 min before meals. All subjects received a 2000 kcal diet/day and participated in supervised walking.
RESULTS: At the end of 8 weeks, body weight and BMI decreased by 5-6% in both groups A and B. Food intake, total cholesterol, low-density lipoproteins, triglycerides and serum leptin levels were significantly reduced in both groups, while high-density lipoprotein levels and excretion of urinary fat metabolites increased in both groups. A marginal or non-significant effect was observed in all parameters in group C.
CONCLUSION: The present study shows that optimal doses of HCA-SX and, to a greater degree, the combination of HCA-SX, NBC and GSE can serve as an effective and safe weight-loss formula that can facilitate a reduction in excess body weight and BMI, while promoting healthy blood lipid levels.
Source：
Preuss HG, Bagchi D, Bagchi M,Rao CV,Dey DK, Satyanarayana S.
PubMed. 2004 May; 6(3):171-80.
www.ncbi.nlm.nih.gov/pubmed/15056124
Super CitriMax is A Highly Effective Adjunct to Healthy Weight Control
Efficacy of a novel calcium/potassium salt of
(-)-hydroxycitric acid in weight control.
Abstract
The weight-loss efficacy of a novel, water-soluble, calcium-potassium salt of (-)-hydroxycitric acid (HCA-SX) was re-examined in 90 obese subjects (BMI: 30-50.8 kg/m2). We combined data from two previously reported randomized, double-blind, placebo-controlled clinical studies in order to achieve a better statistical evaluation based on a larger population. This re-examination of data also allowed us to reflect more intensely on various aspects of weight loss studies. Subjects were randomly divided into three groups: group A received a daily dose of HCA-SX 4, 667 mg (providing 2,800 mg HCA per day); group B was given a daily dose of a combination of HCA-SX 4,667 mg, niacin-bound chromium (NBC) 4 mg (providing 400 microg elemental chromium), and Gymnema sylvestre extract (GSE) 400 mg (providing 100 mg gymnemic acid); and group C received a placebo in three equally divided doses 30-60 min before each meal. All subjects were provided a 2,000 kcal diet/day and participated in a supervised walking program for 30 min/day, 5 days/week. Eighty-two subjects completed the study. At the end of 8 weeks, in group A, both body weight and BMI decreased by 5.4%, low-density lipoprotein and triglycerides levels were reduced by 12.9% and 6.9%, respectively, while high-density lipoprotein levels increased by 8.9%, serum leptin levels decreased by 38%, serotonin levels increased by 44.5% and urinary excretion of fat metabolites increased by 32-109%. Group B demonstrated similar beneficial changes, but generally to a greater extent. No significant adverse effects were observed. The combined results confirm that HCA-SX and, to a greater degree, the combination of HCA-SX plus NBC and GSE reduce body weight and BMI, suppress appetite, improve blood lipid profiles, increase serum leptin and serotonin levels and increase fat oxidation more than placebo. We conclude that dosage levels, timing of administration, subject compliance and bioavailability of HCA-SX significantly affect results and that when taken as directed, HCA-SX is a highly effective adjunct to healthy weight control.
Source：
Preuss HG, Garis RI, Bramble JD, Bagchi D,Bagchi M, Rao CV, Satyanarayana S
PubMed. Int J Clin Pharmacol Res. 2005;25(3):133-44.
www.ncbi.nlm.nih.gov/pubmed/16366421
Super CitriMax – Preuss, et al. Nutr Res. 2004.
Efficacy of a novel, natural extract of (–)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX, niacin-bound chromium and Gymnema sylvestre extract in weight management in human volunteers: a pilot study
Abstract:
In this pilot study, the efficacy of a novel, natural extract of a highly bioavailable, calcium-potassium salt of (–)-hydroxycitric acid (HCA-SX) alone and in combination with a niacin-bound chromium (NBC) and Gymnema sylvestra extract (GSE) was evaluated for weight loss in moderately obese subjects by monitoring changes in body weight, body mass index (BMI), appetite, lipid profiles, serum leptin and serotonin levels, and enhanced excretion of urinary fat metabolites. Garcinia cambogia-derived (–)-hydroxycitric acid (HCA) has been shown to reduce appetite, inhibit fat synthesis and decrease body weight without stimulating the central nervous system. NBC has shown the ability to restore insulin function, metabolize fat, turn protein into muscle, and convert sugar into energy, which plays a role in appetite regulation and facilitates weight loss. Gymnema sylvestre is a traditional herb that helps to promote weight loss possibly through its ability to reduce cravings for sweets and control blood sugar levels. A randomized, double-blind, placebo-controlled human clinical study was conducted in thirty obese subjects (ages 21-50, BMI>26 kg/m2) for eight weeks in Elluru, India. The subjects were randomly divided into three groups (10 subjects/group) and given HCA-SX 4,667 mg (60% HCA providing 2,800 mg HCA/day) (Group A), a combination of HCA-SX 4,667 mg, NBC 4 mg (providing 400 μg elemental Cr) and GSE 400 mg (providing 100 mg gymnemic acid) (Group B), or placebo (Group C) daily in 3 equally divided doses 30-60 min before each meal. This HCA-SX dose was extrapolated from previously conducted in vitro and in vivo studies. In addition, subjects received 2,000 kcal diet/day and underwent a 30 min/day supervised walking program, 5 days/week. At the end of 8 weeks, body weight and BMI decreased by 6.3%, respectively, in Group A. Food intake was reduced by 4%. Total cholesterol, LDL and triglycerides levels were reduced by 6.3%, 12.3% and 8.6%, respectively, while HDL and serotonin levels increased by 10.7% and 40%, respectively. Serum leptin levels were decreased by 36.6%, and the enhanced excretion of urinary fat metabolites, including malondialdehyde (MDA), acetaldehyde (ACT), formaldehyde (FA) and acetone (ACON), increased by 125-258%. Under these same conditions, Group B reduced body weight and BMI by 7.8% and 7.9%, respectively. Food intake was reduced by 14.1%. Total cholesterol, LDL and triglyceride levels were reduced by 9.1%, 17.9% and 18.1%, respectively, while HDL and serotonin levels increased by 20.7% and 50%, respectively. Serum leptin levels decreased by 40.5% and enhanced excretion of urinary fat metabolites increased by 146-281%. Group C reduced body weight and BMI by only 1.6% and 1.7%, respectively, food intake was increased by 2.8%, and LDL, triglycerides and total cholesterol decreased by 0.8%, 0.2% and 0.8%, respectively. HDL were reduced by 4.1% while serum leptin levels were increased by 0.3%, and excretion of urinary fat metabolites did not change in MDA, ACT and FA, and marginally increased in the case of ACON. No adverse effects were observed. Results demonstrate that HCA-SX and, to a greater degree, the combination of HCA-SX, NBC and GSE can serve as safe weight management supplements.
Source：
Harry G Preuss, Debasis Bagchi, Manashi Bagchi, C.V. Sanyasi Rao, S Satyanarayana, Dipak K Dey
Nutrition Research. January 2004 Volume 24, Issue 1, Pages 45–58
www.sciencedirect.com/science/article/pii/S0271531703002215
FAQs
Super CitriMax® is an active ingredient of u-Slim. Super CitriMax® contains 60% hydroxycitric acid (HCA) from the dried fruit rind of Garcinia cambogia. It is uniquely bound to the essential minerals calcium and potassium for maximum stability, solubility, bioavailability and efficacy.
Super CitriMax® is the subject of eight U.S. and international patents and over twenty patents-pending covering more than 160 composition, process and method of use claims.
Super CitriMax® is clinically proven to:
- 1. Reduces body weight three-times greater than diet and exercise alone*
- 2. Reduces BMI three-times greater than diet and exercise alone*
- 3. Increases fat burning*
- 4. Controls appetite*
- 5. Reduces caloric intake by 25%*
- 6. Promotes healthy serotonin levels*
- 7. Supports normal cholesterol levels*
- 8. Good source of calcium*
Super CitriMax is the only HCA ingredient shown to increase levels of serum serotonin, a neurotransmitter involved in appetite control, which helps reduce caloric intake, increase satiety, control portion size and may help address many of the emotional issues overweight people face, including binge-eating.*
Super CitriMax has been shown to burn fat by breaking down the perilipin protein layer surrounding fat cells (only HCA ingredient patented for fat burning). This facilitates the dispersion of fat droplets and the burning of body fat, which may include brown fat, the toughest fat to lose.*
Unlike carb-blockers that inhibit the absorption of carbohydrates, Super CitriMax actually blocks the conversion of carbohydrates into fat and cholesterol at the cellular level by temporarily inhibiting ATP-citrate lyase, the citric acid cleavage enzyme.*
Super CitriMax® is 100% natural and safe to take.*
- Super CitriMax® is derived from the dried fruit rind of Garcinia cambogia, a plant native to South-east Asia, where the dried rind has been used for centuries to make meals more “filling.” Garcinia cambogia is listed in the U.S. Department of Agriculture’s list of perennial edible fruits.
- Super CitriMax® consists of standardized levels of (–)-hydroxycitric acid (HCA), an organic acid similar to citric acid found in citrus fruits, but with remarkably different properties. HCA has been clinically shown to curb appetite, reduce food intake, burn fat and inhibit fat synthesis.
- Super CitriMax® does not stimulate the central nervous system or cause side effects such as sleeplessness, nervousness or rapid heart rate associated with diet stimulants such as caffeine.
Super CitriMax® is the subject of eleven proprietary clinical and sub-clinical studies, including:*
- Efficacy in Humans: Georgetown University Medical Center
- Satiety in Humans: Maastricht University, Dept. Human Biology, Netherlands
- Serotonin in Humans: University of Houston, School of Pharmacy
- Fat Burning/Oxidation-Cell Culture: Ohio State University Medical Center
- Bioavailability in Humans: University of California, Dept. of Nutritional Sciences
- Safety in Animals: Creighton University Medical Center
- Energy Expenditure in Animals: Swiss Institute of Technology, Institute of Animal Science
- Neurotransmitters in Animals: Creighton University Medical Center
- Gene Expression Studies: Ohio State University Medical Center
Super CitriMax® is GRAS (Generally Recognized As Safe) affirmed and the only HCA ingredient affirmed as such by the Burdock Group, the nation’s leading toxicology specialists in evaluating the safety of food and beverage ingredients.
- *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. The information provided on this site is intended for your general knowledge only and is not a substitute for professional medical advice or treatment for specific medical conditions.